LDL Cholesterol (Sampson / NIH) Calculator

About LDL Cholesterol (Sampson / NIH) Calculator

LDL-C by the Sampson equation, valid up to triglycerides of 800 mg/dL. The LDL Cholesterol (Sampson / NIH) Calculator on Picscaler gives you the answer instantly in your browser, with no sign-up.

Inputs: Total cholesterol (mg/dL), HDL cholesterol (mg/dL) and Triglycerides (mg/dL). Results shown: LDL cholesterol (Sampson) and Non-HDL cholesterol.

Formula: LDL = TC/0.948 - HDL/0.971 - (TG/8.56 + TG x nonHDL/2140 - TG^2/16100) - 9.44. Sampson et al. 2020. More accurate than Friedewald at high triglycerides. Estimated, not measured.

This tool is for education and information. It does not replace clinical judgement, so confirm results against your laboratory's reference ranges and local guidelines.

How to use LDL Cholesterol (Sampson / NIH) Calculator

1. Enter Total cholesterol (mg/dL), HDL cholesterol (mg/dL) and Triglycerides (mg/dL).
2. Press Calculate.
3. Read LDL cholesterol (Sampson) and Non-HDL cholesterol in the result table.
4. Use the formula and notes under the result to check the working.

Frequently asked questions

Is LDL Cholesterol (Sampson / NIH) Calculator free?

Yes. LDL Cholesterol (Sampson / NIH) Calculator is completely free to use on Picscaler.

Do I need to create an account?

No. You can use it straight away without signing up.

Is my data safe?

Your input is processed in your browser on your own device and is not uploaded to Picscaler.

Can I use it for medical decisions?

No. It is an educational aid and does not replace professional medical judgement.